纠正人类胚胎中的致病基因突变
Correction of a pathogenic gene mutation in human embryos. Nature. 2017;548(7668):413-419. PMID: 28783728.
携带致病性线粒体 DNA 突变的人类卵母细胞中的线粒体替代
Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations. Nature. 2016;540(7632):270-275. PMID: 27919073.
成人来源的人 iPSC 中体细胞线粒体 DNA 突变的年龄相关积累
Age-Related Accumulation of Somatic Mitochondrial DNA Mutations in Adult-Derived Human iPSCs. Cell Stem Cell. 2016;18(5):625-636. PMID: 27151456.
DNA 疾病患者多能细胞的代谢拯救
Metabolic rescue in pluripotent cells from patients with mtDNA disease. Nature. 2015;524(7564):234-238. PMID: 26176921.
由于重编程机制导致的人类多能细胞异常
Abnormalities in human pluripotent cells due to reprogramming mechanisms. Nature. 2014;511(7508):177-183. PMCID: PMC4898064.
通过双细胞小鼠胚胎的间期细胞质进行核重编程
Nuclear reprogramming by interphase cytoplasm of two-cell mouse embryos. Nature. 2014;509(7498):101-104. PMCID: PMC4124901.
体细胞核移植衍生的人胚胎干细胞
Human embryonic stem cells derived by somatic cell nuclear transfer. Cell. 2013;153(6):1228-1238. PMCID: PMC3772789.
遗传性线粒体疾病的种系基因治疗
Towards germline gene therapy of inherited mitochondrial diseases. Nature. 2013;493(7434):627-631. PMCID: PMC3561483.
灵长类动物后代和胚胎干细胞中的线粒体基因替代
Mitochondrial gene replacement in primate offspring and embryonic stem cells. Nature. 2009;461(7262):367-372. PMCID: PMC2774772.
携带致病性线粒体 DNA 突变的人类卵母细胞中的线粒体替代
Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations. Nature. 2016;540(7632):270-275. PMID: 27919073.